Finding a rhyme and reason to CRISPR-Cas9’s mutations: Investigators predict CRISPR-Cas9 gene disruptions with accuracy, experimentally confirm findings in disease models

Since the early days of CRISPR-Cas9, researchers have known that this gene editing technology is excellent for breaking things. With

Potential therapy for treatment-resistant hypothyroidism proves effective in lab study: Novel coordination of thyroid hormone with zinc promotes slow release of active hormone to supplement standard therapy

A new “metal-coordinated” drug-delivery technology potentially could be used to supplement the standard therapy for hypothyroidism, which affects nearly 10

Why randomized trials for proton therapy are difficult to complete (and what we can do about it): Experts lay out strategies to tackle key barriers in proton research

Randomized clinical trials are the gold standard of cancer research and can shed light on whether innovative, new therapies with

Model automates molecule design to speed drug development: Machine-learning model could help chemists make molecules with higher potencies, much more quickly.

Designing new molecules for pharmaceuticals is primarily a manual, time-consuming process that’s prone to error. But MIT researchers have now

Cells stop dividing when this gene kicks into high gear: Discovery — centered on a gene called CD36 — illuminates a process tied to the aging of cells and organisms

Scientists seeking to unlock the secrets of cellular aging have identified a gene that triggers senescence, a phenomenon in which